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REVIEW ARTICLE
Year : 2020  |  Volume : 7  |  Issue : 4  |  Page : 232-235

Ideal tissue regeneration option following periapical surgery


1 Guru Nanak Dev Dental College and Research Institutes, Sunam, Punjab, India
2 Panineeya Mahavidyalaya Institute of Dental Sciences and Research Center, Hyderabad, Telangana, India
3 Department of Paediatric Dentistry, Ministry of Health, King Khaled Hospital, Riyadh, Saudi, Arabia
4 Department of Oral and Maxillofacial Surgeon, SGT University, Jhajjar, Haryana, India
5 Department of Oral and Maxillofacial Surgeon, Babu Banarasi Das College of Dental Sciences, Lucknow, Uttar Pradesh, India

Correspondence Address:
Malti Tuli
Guru Nanak Dev Dental College and Research Institutes, Sunam, Punjab
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jdrr.jdrr_37_20

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Optimal tissue regeneration in the periapical region is essential following a periapical surgery. Literature shows that augmenting the osseous defect with artificial bone substitutes, growth factors, or barrier membranes acts as critical factors influencing the healing following surgical intervention. For the regeneration of tissues following periapical surgery, an essential requisite is progenitor/stem cells. Few studies have shown that simple use of a membrane barrier and/or bone graft following surgery might not produce adequate tissue regeneration. Literature clearly shows that few substitutes are capable of generating progenitor/stem cells and induce the undifferentiated mesenchymal cells to differentiate. Hence, this review is intended to throw light on whether tissue regeneration with the aid of bone grafts coupled with a membrane barrier will suffice or is there a need for recruiting progenitor/stem cells.


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