• Users Online: 898
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
DPU: INTERDISCIPLINARY CONFERENCE
Year : 2020  |  Volume : 7  |  Issue : 5  |  Page : 95-97

Chitosan and stemcells: A synchrony for regeneration


1 Departments of Oral and Maxillofacial Surgery, Dr. D. Y. Patil Dental College and Hospital, Dr. D. Y. Patil Vidyapeeth, Pimpri, Pune, Maharashtra, India
2 Department of Pharmaceutical Chemistry, Dr. D. Y. Patil Institute of Pharmaceutical Sciences and Research, Dr. D. Y. Patil Vidyapeeth, Pimpri, Pune, Maharashtra, India
3 Department of Research, Dr. D. Y. Patil Vidyapeeth, Pimpri, Pune, Maharashtra, India

Correspondence Address:
Lakshmi Shetty
Department of Oral and Maxillofacial Surgery, Dr. D. Y. Patil Dental College and Hospital, Dr. D. Y. Patil Vidyapeeth, Pimpri, Pune - 411 018, Maharashtra
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jdrr.jdrr_75_19

Rights and Permissions

Background: Stem cells have infinite self-renewing capacity and potential for differentiation and regeneration. Human dental pulp stem cells (hDPSCs) from the extracted tooth are a rich source of mesenchymal stem cells, which can regenerate into osteogenic, chondrogenic, or adipogenic lineages. Chitosan which is a porous structure may have the ability to house these stem cells for regeneration. This study was to determine the effectiveness of growth of hDPSCs in the chitosan scaffolds. Methodology: The study was conducted in the Regenerative Medicine Laboratory, Dr. D.Y. Patil Dental College and Hospital in coordination with Department of Oral and Maxillofacial Surgery, Dr. D.Y. Patil Dental College and Hospital, and Dr. D.Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune. The chitosan scaffolds were prepared at Dr. D.Y. Patil Institute of Pharmaceutical Sciences and Research. Twenty extracted human dental pulp were used for stem cells differentiation. Results: The chitosan scaffold showed an excellent growth of chondrogenic cells per unit in × 40 magnification, and hence, this sets a benchmark for hDPSC study in India. Conclusion: hDPSCs in porous chitosan scaffolds help us to regenerate chondrogenic cells and will initiate the research in an interdisciplinary approach toward cartilage regeneration.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed77    
    Printed2    
    Emailed0    
    PDF Downloaded10    
    Comments [Add]    

Recommend this journal